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2026/08/20Clicks：7
For pharmaceutical cleanroom applications, hose selection should be based on the actual fluid, pressure, temperature, cleanliness requirements, and installation conditions—not simply on chemical resistance.
For one pharmaceutical filtration system project, the end user required a hose for pharmaceutical cleaning water and Water for Injection (WFI). The fluid was mainly neutral, with relatively low acid and alkali concentrations. A chemical hose was not suitable for the application.
After reviewing the operating conditions, CJan Fluid Technology Co., Ltd. recommended the SQ Platinum-Cured Silicone Steel Wire Reinforced Hose.
The selected 1.5-inch SQ hose can meet the project's requirements for pressure, temperature, flexibility, and clean fluid transfer.
The customer specializes in the R&D, manufacturing, system integration, and on-site installation of filtration systems.
For this project, the equipment was installed in a pharmaceutical plant cleanroom. The hose is used mainly for transferring:
The customer specifically required a hose suitable for this type of clean application rather than a conventional chemical transfer hose.
The main operating conditions were:
| Item | Requirement |
|---|---|
| Industry | Pharmaceutical |
| Application Area | Pharmaceutical Cleanroom |
| Medium | Cleaning Water / WFI |
| Medium Characteristics | Mainly Neutral |
| Acid/Alkali Concentration | Low |
| Working Pressure | 1 MPa |
| Ambient Temperature | -10°C |
| Hose Size | 1.5 inch |
| Vacuum Resistance | Not Required |
| Recommended Product | SQ Platinum-Cured Silicone Hose |
The key point in this project was the actual process medium.
Although the application occasionally involves low-concentration acidic or alkaline solutions, the main media are pharmaceutical cleaning water and WFI. The operating conditions do not represent a typical high-corrosion chemical transfer application.
Therefore, choosing a chemical hose simply because the application involves some acid or alkali would not necessarily be the best solution.
For this project, the focus was placed on:
Based on these requirements, a platinum-cured silicone hose was considered more appropriate than a conventional chemical hose.
The recommended product is:
The SQ series combines a platinum-cured silicone inner layer with a reinforced structure to provide a balance of flexibility and mechanical strength.
For this project, the selected 1.5-inch SQ hose was evaluated against the customer's 1 MPa working pressure and cleanroom application requirements.
Platinum-cured silicone is widely used in applications where cleanliness and material stability are important.
Compared with ordinary industrial rubber hoses, platinum-cured silicone provides several advantages for pharmaceutical and hygienic applications.
The silicone material is suitable for a range of clean fluid transfer applications in pharmaceutical, biotechnology, food, and related industries.
For pharmaceutical equipment, the material itself is an important part of the overall fluid path.
One of the practical advantages of silicone hose is its flexibility.
In pharmaceutical filtration systems, equipment layouts can vary considerably from one installation to another. Flexible hose can make it easier to connect:
This can also simplify installation and maintenance.
The SQ hose uses a reinforced construction to improve its pressure resistance and dimensional stability.
The project requires a working pressure of:
1 MPa
Therefore, a reinforced silicone hose is more suitable than an unreinforced silicone tube for this application.
The final hose specification should always be confirmed according to the selected diameter, temperature, connection method, and actual operating pressure.
The project has an ambient temperature of:
-10°C
Temperature is an important consideration when selecting a silicone hose because the surrounding environment can affect hose flexibility and mechanical performance.
The SQ hose was evaluated according to the customer's actual temperature requirements.
Filtration systems are often assembled from multiple pieces of equipment.
The actual installation may involve:
A flexible hose can make these connections easier to install compared with rigid piping.
For this reason, hose selection should consider not only pressure and temperature, but also the actual installation environment.
For this application, the selection process focused on the following factors:
The main media are pharmaceutical cleaning water and WFI, with relatively low concentrations of acid and alkali.
The required working pressure is:
1 MPa
This makes a reinforced hose construction necessary.
The ambient temperature is:
-10°C
The hose needs to maintain suitable flexibility and performance under the specified conditions.
The customer does not require vacuum resistance.
Therefore, there is no need to select a hose specifically designed for vacuum service.
The required hose size is:
1.5 inch
Since the application is primarily clean water and pharmaceutical fluid transfer rather than high-concentration chemical transfer, the SQ platinum-cured silicone hose was recommended.
The SQ series can be considered for various clean fluid applications, depending on the actual operating conditions.
Typical applications include:
The actual hose specification should always be confirmed based on the medium, concentration, temperature, pressure, connection, and applicable regulatory requirements.
Choosing a pharmaceutical hose should start with the actual process conditions.
Is the medium WFI, purified water, cleaning solution, buffer, chemical solution, or another process fluid?
What is the normal working pressure and maximum pressure?
Consider both the fluid temperature and the ambient temperature.
Determine whether the application requires a hygienic or high-purity hose.
Consider the minimum bend radius and the available installation space.
Confirm whether the system will experience suction or negative pressure.
The hose should also be matched with the required sanitary fitting, clamp, barb, or other connection method.
This project was for a pharmaceutical plant cleanroom, where the customer needed a hose for pharmaceutical cleaning water and WFI transfer.
The main conditions were:
1.5-inch size + 1 MPa working pressure + -10°C ambient temperature + no vacuum requirement
The media were mainly neutral, with low concentrations of acid and alkaline solutions.
After reviewing the application, CJan Fluid Technology recommended:
The SQ hose provides a combination of platinum-cured silicone material, reinforcement, flexibility, and pressure capability, making it a suitable option for this type of pharmaceutical clean fluid application.
The key to the selection was not simply choosing the hose with the highest chemical resistance. Instead, the hose was matched to the actual medium and operating environment.
CJan Fluid Technology Co., Ltd. provides hose and fluid connection solutions for pharmaceutical, biopharmaceutical, semiconductor, food, chemical, and new energy applications.
Our product range includes:
CJan works with customers to select suitable products based on the actual medium, pressure, temperature, size, cleanliness requirements, flexibility, and installation conditions.
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